The Peter Schick Foundation has submitted all the necessary data to obtain an IND number from the FDA for the product Alpha Sun. Alpha Sun is made by Simplexity Health of Klamath Falls, Oregon. The product, a bone marrow stem cell stimulator, increases the number of circulating stem cells 20-30% two hours after oral ingestion of l000mg/day. The foundation hopes to test the product in a number of clinical studies, namely Type 2 Diabetes and HIV+ patients who are virologically suppressed on antiretroviral therapy. Additional studies in the works include testing the product in osteoarthitis patients, osteoporosis patients, prostatitis patients, Acne patients, post-operative inguinal hernia patients, carpal tunnel patients, and Cardiac rehabilitation patients. The product has significant anti inflammatory capabilities, is a mood elevator, and has a carbohydrate that directs bone marrow stem cells to the point of inflammation and injury where it initiates repair of damage caused by an inflammatory process. Two initial trials will be done for Type 2 Diabetes, and another for HIV+ patients who are virologically suppressed on antiretroviral therapy.
The Peter Schick Foundation and Simplexity Health are forming a partnership to study in clinical trials Aphanizomenon Flos-Aquae (termed AFA), which is the major component of the product Alpha Sun.
A C corporation will be formed with available common shares of stock. If you wish to learn more about the offering or donate to the non-profit 501(c)(3) foundation, please email schickpm@aol.com or contribute by mail to the Schick Foundation, 1223 Wilshire Blvd. #1007, Santa Monica, CA 90403.
The Perilous Success: What if the new HIV prevention methods work?
The Perilous Success: What if the new HIV prevention methods work?
AIDS Weekly
September 15, 2009
Within a couple of years, we may know if two crucial new HIV prevention approaches will work. If they do, what then? Who will pay for them, who will use them, and will their use have a positive or negative impact on the epidemic?
This was a debate carried on at the IAS conference advocacy coalition as they looked at the possibility of microbicides and pre-exposure prophylaxis(PrEP).
Microbicides are a long way from being a preventative approach to HIV infection, both because of scientific and behavioral concerns. Pre-exposure prophylaxis also has strong behavioral concerns even if it is accepted scientifically.
The only real way of prevention is to treat everyone with antiretroviral meds in a high incidence area.
AIDS Weekly
September 15, 2009
Within a couple of years, we may know if two crucial new HIV prevention approaches will work. If they do, what then? Who will pay for them, who will use them, and will their use have a positive or negative impact on the epidemic?
This was a debate carried on at the IAS conference advocacy coalition as they looked at the possibility of microbicides and pre-exposure prophylaxis(PrEP).
Microbicides are a long way from being a preventative approach to HIV infection, both because of scientific and behavioral concerns. Pre-exposure prophylaxis also has strong behavioral concerns even if it is accepted scientifically.
The only real way of prevention is to treat everyone with antiretroviral meds in a high incidence area.
India says no to HIV drug patents
India says no to HIV drug patents
Nature News
September 3, 2009
India has rejected applications for patents from two US drug pharmaceutical companies for two AIDS drugs which could mean that more poor people in poor countries will have access to life saving medicines. The decisions are the latest in a string of legal victories for Cipla, India's largest generic drug maker. The move could also signal that patent offices in emerging economies are set to take a tougher line than industrialized countries on which drugs deserve patents. The drugs rejected are Gilead's drug Tenofovir and Tibotec's drug Darunavir.
Nature News
September 3, 2009
India has rejected applications for patents from two US drug pharmaceutical companies for two AIDS drugs which could mean that more poor people in poor countries will have access to life saving medicines. The decisions are the latest in a string of legal victories for Cipla, India's largest generic drug maker. The move could also signal that patent offices in emerging economies are set to take a tougher line than industrialized countries on which drugs deserve patents. The drugs rejected are Gilead's drug Tenofovir and Tibotec's drug Darunavir.
Schick Foundation Looks To Partner With Simplexity
Schick Foundation Looks To Partner With Simplexity
The Peter Schick Foundation is forming a partnership with Simplexity Health of Klamath Falls, Oregon. Simplexity Health is the maker and distributor of Blue Green Algae, which is marketed under the brand name Alpha Sun. Its main component is the algae aphanizomenon-flos-aquae (AFA). The agreement reached in principal will allow The Schick Foundation to finally submit the necessary data to the FDA to get an IND number. This should lead to rapid approval of the IND number, and allow the foundation to start its clinical research protocols in virologically suppressed HIV+ patients being treated with 1000 mg of AFA per day in addition to their suppressive antiretroviral treatment.
These are patients naive to antiretroviral treatment with low levels of virus. The foundation will also study Type 2 Diabetes and the effects of AFA on this common disease state which causes more morbidity and hospitalization costs than any other disease in this country. The two organizations – Simplexity Health and the Peter Schick Foundation – will form a for-profit/non-profit entity which is being formed by a local law firm that specializes in working with nonprofit agencies. This will allow both organizations to benefit greatly.
To help with the costs of these two revolutionary protocols, tax-deductible donations can be made to the Peter Schick Foundation, 1223 Wilshire Blvd #1007, Santa Monica, California, 90403.
The Peter Schick Foundation is forming a partnership with Simplexity Health of Klamath Falls, Oregon. Simplexity Health is the maker and distributor of Blue Green Algae, which is marketed under the brand name Alpha Sun. Its main component is the algae aphanizomenon-flos-aquae (AFA). The agreement reached in principal will allow The Schick Foundation to finally submit the necessary data to the FDA to get an IND number. This should lead to rapid approval of the IND number, and allow the foundation to start its clinical research protocols in virologically suppressed HIV+ patients being treated with 1000 mg of AFA per day in addition to their suppressive antiretroviral treatment.
These are patients naive to antiretroviral treatment with low levels of virus. The foundation will also study Type 2 Diabetes and the effects of AFA on this common disease state which causes more morbidity and hospitalization costs than any other disease in this country. The two organizations – Simplexity Health and the Peter Schick Foundation – will form a for-profit/non-profit entity which is being formed by a local law firm that specializes in working with nonprofit agencies. This will allow both organizations to benefit greatly.
To help with the costs of these two revolutionary protocols, tax-deductible donations can be made to the Peter Schick Foundation, 1223 Wilshire Blvd #1007, Santa Monica, California, 90403.
Mediterranean Diet Improves Glycemic Control in Patients with Type 2 Diabetes
Mediterranean Diet Improves Glycemic Control in Patients with Type 2 Diabetes
Annals of Internal Medicine
August 2009
A Mediterranean-style diet may be better than a low-fat diet for helping patients with type 2 diabetes, and delay treatment with anihyperglycemic drugs.
Italian researchers randomized some 200 overweight patients with newly diagnosed diabetes to either a Mediterranean-style diet (less than 50% of calories from carbohydrates) or a low-fat diet (less than 30% of calories from fat).
At four years, fewer patients on the Mediterranean diet than on the low-fat diet had HbA1C levels greater than 7%, thus requiring treatment with anihyperglycemic drugs (44% vs 70%). The Mediterranean diet group also had a larger increase in insulin sensitivity, greater weight loss, and reduced coronary risk factors.
The authors say the Mediterranean diet's effects could be explained by the high consumption of monounsaturated fatty acids, which may increase insulin sensitivity. They conclude:
"The findings reinforce the message that benefits of lifestyle interventions should not be overlooked.”
Diet and exercise are the hallmarks of treating type 2 diabetes. This includes patients with HIV.
Schick Research is conducting a study that may prove that blue-green algae, because it changes the milieu of the GI tract and the pancreas, may be used to control type 2 diabetes. If our study is proven successful, it may replace oral insulin in these patients.
Annals of Internal Medicine
August 2009
A Mediterranean-style diet may be better than a low-fat diet for helping patients with type 2 diabetes, and delay treatment with anihyperglycemic drugs.
Italian researchers randomized some 200 overweight patients with newly diagnosed diabetes to either a Mediterranean-style diet (less than 50% of calories from carbohydrates) or a low-fat diet (less than 30% of calories from fat).
At four years, fewer patients on the Mediterranean diet than on the low-fat diet had HbA1C levels greater than 7%, thus requiring treatment with anihyperglycemic drugs (44% vs 70%). The Mediterranean diet group also had a larger increase in insulin sensitivity, greater weight loss, and reduced coronary risk factors.
The authors say the Mediterranean diet's effects could be explained by the high consumption of monounsaturated fatty acids, which may increase insulin sensitivity. They conclude:
"The findings reinforce the message that benefits of lifestyle interventions should not be overlooked.”
Diet and exercise are the hallmarks of treating type 2 diabetes. This includes patients with HIV.
Schick Research is conducting a study that may prove that blue-green algae, because it changes the milieu of the GI tract and the pancreas, may be used to control type 2 diabetes. If our study is proven successful, it may replace oral insulin in these patients.
Miracle Superfood: Wild Blue-Green Algae
Miracle Superfood: Wild Blue-Green Algae
Gillian McKeith, Ph.D.
Keats Good Health Guide
The nutrient powerhouse that stimulates the immune system, boosts brain power and guards against disease.
Many of you have asked what the components are of Blue Green Algae. The body is capable of utilizing virtually all of the algae's nutrients. When making a conventional multiple vitamin with mineral, the body is capable of utilizing virtually all of the algae nutrients. When taking a conventional multiple vitamin with minerals, the body may only absorb a small fraction of the actual nutrient dosages.
The component of AFA algae is as follows:
Minerals. One of the greatest contributions of Blue-Green AFA algae is a full spectrum of minerals. Minerals are the framework for our bodies, critical to our overall mental and physical well-being. Bones, teeth, muscle, blood, nerve cells, tissues and internal fluids all contain varying quantities of minerals. They help to build the skeletal structure, regulate the heart, balance internal pressure of body flies, nerve response and oxygen transport from the lungs to the tissues. Minerals act as a catalyst for many biological reactions within the body including muscle response, digestion, metabolism of nutrients in foods, and transmission of messages through the nervous systems. Minerals help to maintain the body's delicate water balance, allowing the mental and physical processes to function properly. They keep blood and tissue fluids from becoming too acid or too alkaline, the balancing the body's PH. Minerals permit other nutrients to pass into the bloodstream.
The problem with minerals, however, is that they can only be supplied through the food one eats. The different minerals in AFA are Boron, Calcium, Chloride, Chromium, Cobalt, Copper, Fluoride, Germanium, Iodine, Iron, Magnesium Manganese, Molybdenum, Nickel, Phosphorous, Potassium, Selenium, Silicon, Sodium, Tin, Titanium Vanadium and Zinc. These are not present in any toxic amounts.
Proteins and amino acids. Wild blue-green algae is an exceptionally high source of proteins (60%) nearly identical to the human body's protein composition. The quality of the protein in AFA algae is superior to that of most other plant or animal protein sources, being derived from all eight essential amino acids. It is important for general good health of the skin, hair, nails, brain, ligaments, bones, teeth, hormones, sex glands, and enzymes that we eat foods with. If one of the eight essential amino acids is missing, then the body cannot make protein.
The essential amino acids that AFA has is isoleucine, leucine, lysine, methionine, tryptophan, threonine, phenyalanine, and valine. The semi-essential amino acids that AFA has are arginine and histidine. The non-essential amino acids that AFA has is Alanine, aspartic acid, cystine, glutamic acid, proline, serine, and tyrosine.
AFA is rich in all kinds of botanical pigments. A pigment is a molecular capsule of absorbing wavelength of light which is then reflected as a recognizable color. AFA has Chlorophyll – a permanent pigment. Chlorophyll is the livelihood of AFA algae. It is similar in molecular structure to heme, the oxygen carrying and pigment of human blood. Phycocyanines are present in AFA. Phycocyanin is the pigment which gives wild blue-green algae its blue base. It is a protein which has been shown to inhibit the formation of "cancer colonies". These pigments operate with billirubin to keep the liver functioning. Phycocyanin helps draw gogether amino acids for neurotransmitter function, which may increase mental capacity.
Wild blue-green algae contains approximately four percent RNA/DNA. The RNA/DNA (nucleic acid) is needed for growth of body tissues and to make new cells, repair damaged cells, and for growth of body tissue. As people get older, the levels of RNA/DNA decrease. If you do not have enough RNA/DNA, you may suffer the consequences of a weak immune system and ultimately age prematurely. Inferior eating habits, pollution, and stress can deplete your RNA/DANA quotient. Keeping the RNA/DNA levels at a consistent level is important if you want to retard your cells destruction, enhance immunity, and regenerate your body.
Lipids, through essential fatty acids, are highly represented in blue-green algae. These lipids are critical for life itself and provide the most concentrated source of energy for the body. Fatty acids function as carriers for vitamins A, E, and K. Lipids within AFA can prevent the skin and other bodily tisssues from becoming dry and scaly. The omega-3 fatty acids are known to help prevent heart diseasse, reduce serum cholesterol and raise HDL (good cholesterol) in addition to improving brain function.
Wild blue-green algae is one of the highest known natural sources of beta-carotene. Beta-carotene is a powerful antioxidant and anti-infective protective agent against skin disorders, night blindness, allergies, and immune system dysfunction.
Finally, AFA – with its particle L-selectin Ligan – releases adult bone marrow stem cells from the bone marrow of people who take it. Stem cells are the center of the universe for the immune system and can control with help all immune cellular in antibody function.
Gillian McKeith, Ph.D.
Keats Good Health Guide
The nutrient powerhouse that stimulates the immune system, boosts brain power and guards against disease.
Many of you have asked what the components are of Blue Green Algae. The body is capable of utilizing virtually all of the algae's nutrients. When making a conventional multiple vitamin with mineral, the body is capable of utilizing virtually all of the algae nutrients. When taking a conventional multiple vitamin with minerals, the body may only absorb a small fraction of the actual nutrient dosages.
The component of AFA algae is as follows:
Minerals. One of the greatest contributions of Blue-Green AFA algae is a full spectrum of minerals. Minerals are the framework for our bodies, critical to our overall mental and physical well-being. Bones, teeth, muscle, blood, nerve cells, tissues and internal fluids all contain varying quantities of minerals. They help to build the skeletal structure, regulate the heart, balance internal pressure of body flies, nerve response and oxygen transport from the lungs to the tissues. Minerals act as a catalyst for many biological reactions within the body including muscle response, digestion, metabolism of nutrients in foods, and transmission of messages through the nervous systems. Minerals help to maintain the body's delicate water balance, allowing the mental and physical processes to function properly. They keep blood and tissue fluids from becoming too acid or too alkaline, the balancing the body's PH. Minerals permit other nutrients to pass into the bloodstream.
The problem with minerals, however, is that they can only be supplied through the food one eats. The different minerals in AFA are Boron, Calcium, Chloride, Chromium, Cobalt, Copper, Fluoride, Germanium, Iodine, Iron, Magnesium Manganese, Molybdenum, Nickel, Phosphorous, Potassium, Selenium, Silicon, Sodium, Tin, Titanium Vanadium and Zinc. These are not present in any toxic amounts.
Proteins and amino acids. Wild blue-green algae is an exceptionally high source of proteins (60%) nearly identical to the human body's protein composition. The quality of the protein in AFA algae is superior to that of most other plant or animal protein sources, being derived from all eight essential amino acids. It is important for general good health of the skin, hair, nails, brain, ligaments, bones, teeth, hormones, sex glands, and enzymes that we eat foods with. If one of the eight essential amino acids is missing, then the body cannot make protein.
The essential amino acids that AFA has is isoleucine, leucine, lysine, methionine, tryptophan, threonine, phenyalanine, and valine. The semi-essential amino acids that AFA has are arginine and histidine. The non-essential amino acids that AFA has is Alanine, aspartic acid, cystine, glutamic acid, proline, serine, and tyrosine.
AFA is rich in all kinds of botanical pigments. A pigment is a molecular capsule of absorbing wavelength of light which is then reflected as a recognizable color. AFA has Chlorophyll – a permanent pigment. Chlorophyll is the livelihood of AFA algae. It is similar in molecular structure to heme, the oxygen carrying and pigment of human blood. Phycocyanines are present in AFA. Phycocyanin is the pigment which gives wild blue-green algae its blue base. It is a protein which has been shown to inhibit the formation of "cancer colonies". These pigments operate with billirubin to keep the liver functioning. Phycocyanin helps draw gogether amino acids for neurotransmitter function, which may increase mental capacity.
Wild blue-green algae contains approximately four percent RNA/DNA. The RNA/DNA (nucleic acid) is needed for growth of body tissues and to make new cells, repair damaged cells, and for growth of body tissue. As people get older, the levels of RNA/DNA decrease. If you do not have enough RNA/DNA, you may suffer the consequences of a weak immune system and ultimately age prematurely. Inferior eating habits, pollution, and stress can deplete your RNA/DANA quotient. Keeping the RNA/DNA levels at a consistent level is important if you want to retard your cells destruction, enhance immunity, and regenerate your body.
Lipids, through essential fatty acids, are highly represented in blue-green algae. These lipids are critical for life itself and provide the most concentrated source of energy for the body. Fatty acids function as carriers for vitamins A, E, and K. Lipids within AFA can prevent the skin and other bodily tisssues from becoming dry and scaly. The omega-3 fatty acids are known to help prevent heart diseasse, reduce serum cholesterol and raise HDL (good cholesterol) in addition to improving brain function.
Wild blue-green algae is one of the highest known natural sources of beta-carotene. Beta-carotene is a powerful antioxidant and anti-infective protective agent against skin disorders, night blindness, allergies, and immune system dysfunction.
Finally, AFA – with its particle L-selectin Ligan – releases adult bone marrow stem cells from the bone marrow of people who take it. Stem cells are the center of the universe for the immune system and can control with help all immune cellular in antibody function.
AIDS Study on antiretroviral therapy initiation
AIDS Study on antiretroviral therapy initiation
The objective of this study was to examine HIV specific CD8+ T cells from patients with primary HIV infection and other antiretroviral therapy initiation, which were evaluated for CD 127 expression and proliferating capacity and were compared with cells from chronically-infected patients including long-term nonprogressors and HIV elite controllers.
Thirty patients were studied with primary HIV infection and 33 patients were studied with chronic HIV infection including nonprogressors and elite controllers. HIV-specific CD8+ cells were identified by costaining with HIV human leukocyte antigen Class 1 pentamers. CD127 expression was assed by flow cytometry and cell proliferation for carboxyfluorescein succinimidyl ester labeling.
The results showed that during Primary HIV infection most HIV specific CD8+ T cells coexpressed CD27 and CD45RO and were highly activated. Their CD127 expression was very low and correlated negatively with both HIV RNA and DNA levels and with expression of the activation marker CD38. CD127 expression correlated positively with CD4 cell count. Some CD127 expression was observed in the two groups of chronically-infected nonprogressors. CD127 expression on HIV specific CD8+ T cells increased in early-treated primary HIV patients, matching levels similar to those observed in nonprogoressors. In parallel, these cells acquired strong proliferating capacity. No change in CD127 expression or proliferative potential was observed in untreated patients.
The conclusion of this study was that early antiretroviral therapy initiation enhances CD127 expression on HIV-specific CD8+ T cells, reaching levels similar to those observed in aviremic nonprogressors and restores their proliferative capacity allowing them to fight HIV.
This is an interesting study. The only problem is that early HIV infection is hardly ever found. Most patients have well-established infections when they are discovered to be HIV positive and some of them are discovered late in the course of HIV infection.
The objective of this study was to examine HIV specific CD8+ T cells from patients with primary HIV infection and other antiretroviral therapy initiation, which were evaluated for CD 127 expression and proliferating capacity and were compared with cells from chronically-infected patients including long-term nonprogressors and HIV elite controllers.
Thirty patients were studied with primary HIV infection and 33 patients were studied with chronic HIV infection including nonprogressors and elite controllers. HIV-specific CD8+ cells were identified by costaining with HIV human leukocyte antigen Class 1 pentamers. CD127 expression was assed by flow cytometry and cell proliferation for carboxyfluorescein succinimidyl ester labeling.
The results showed that during Primary HIV infection most HIV specific CD8+ T cells coexpressed CD27 and CD45RO and were highly activated. Their CD127 expression was very low and correlated negatively with both HIV RNA and DNA levels and with expression of the activation marker CD38. CD127 expression correlated positively with CD4 cell count. Some CD127 expression was observed in the two groups of chronically-infected nonprogressors. CD127 expression on HIV specific CD8+ T cells increased in early-treated primary HIV patients, matching levels similar to those observed in nonprogoressors. In parallel, these cells acquired strong proliferating capacity. No change in CD127 expression or proliferative potential was observed in untreated patients.
The conclusion of this study was that early antiretroviral therapy initiation enhances CD127 expression on HIV-specific CD8+ T cells, reaching levels similar to those observed in aviremic nonprogressors and restores their proliferative capacity allowing them to fight HIV.
This is an interesting study. The only problem is that early HIV infection is hardly ever found. Most patients have well-established infections when they are discovered to be HIV positive and some of them are discovered late in the course of HIV infection.
The Top 18 FAT Fighting Foods
The Top 18 FAT Fighting Foods
Patrick Tsakude, LA Health
August 2009
Increase your body's fat-burning power by eating these top-fat-fighting foods. #1 Oatmeal, #2 Leafy Greens, #3 Olive oil, #4 Garlic, #5 Tomatoes, #6 Nuts, #7 Cayenne, #8 Turmeric, #9 Cinnamon, #l0 Flax seeds, #11 Apple, #12 Beans, #13 Green Tea, #14 Grapefruit, #15 Broccoli, #16 Lean Turkey, #17 Hot Sauce, #18 Soup.
Patrick Tsakude, LA Health
August 2009
Increase your body's fat-burning power by eating these top-fat-fighting foods. #1 Oatmeal, #2 Leafy Greens, #3 Olive oil, #4 Garlic, #5 Tomatoes, #6 Nuts, #7 Cayenne, #8 Turmeric, #9 Cinnamon, #l0 Flax seeds, #11 Apple, #12 Beans, #13 Green Tea, #14 Grapefruit, #15 Broccoli, #16 Lean Turkey, #17 Hot Sauce, #18 Soup.
Steroids Might Relieve Sore Throat Pain
Steroids Might Relieve Sore Throat Pain
Journal Watch
August 28, 2009
A meta-analysis shows that a single dose of steroids, given in addition to standard antibiotics, hastens resolution of pain in adults with exudative pharyngitis or bacterial pharyngitis. There are many over-the-counter drugs that do the same thing (relieve sore throat pain).
Having doctors prescribe steroids as a one time dose will just increase medical costs, might lead to prolonged use of steroids in some patients, and certainly sore throats can be treated successfully and without pain, without steroids.
Journal Watch
August 28, 2009
A meta-analysis shows that a single dose of steroids, given in addition to standard antibiotics, hastens resolution of pain in adults with exudative pharyngitis or bacterial pharyngitis. There are many over-the-counter drugs that do the same thing (relieve sore throat pain).
Having doctors prescribe steroids as a one time dose will just increase medical costs, might lead to prolonged use of steroids in some patients, and certainly sore throats can be treated successfully and without pain, without steroids.
FDA Warning
FDA Warning
Etravirine, an antiretroviral, has been linked to several skin and hypersensitivity reactions.
Etravirine, (Intelence), a valuable antiretroviral drug has been associated with severe skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, and hypersensitivity reactions characterized by rash. Patients experiencing any of these signs or symptoms should discontinue use of the drug immediately according to the agency.
The FDA does not state how many people experience this complication. The box label had these same reations as very rare. This is exactly the type of meddling that the FDA is doing these days. Many companies are scared off this type of regulatory behavior. It is time for a change in the FDA.
Etravirine, an antiretroviral, has been linked to several skin and hypersensitivity reactions.
Etravirine, (Intelence), a valuable antiretroviral drug has been associated with severe skin reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme, and hypersensitivity reactions characterized by rash. Patients experiencing any of these signs or symptoms should discontinue use of the drug immediately according to the agency.
The FDA does not state how many people experience this complication. The box label had these same reations as very rare. This is exactly the type of meddling that the FDA is doing these days. Many companies are scared off this type of regulatory behavior. It is time for a change in the FDA.
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